Methodology. (Last updated: 1/25/25)
| Rank | Player | Years | Country |
| 1 | Novak Djokovic | 2003-active | Serbia |
| 2 | Roger Federer | 1998-2022 | Switzerland |
| 3 | Rafael Nadal | 2001-active | Spain |
| 4 | Pete Sampras | 1988-2002 | USA |
| 5 | Rod Laver | 1956-1979 | Australia |
| 6 | Björn Borg | 1973-1984, 1991-1993 | Sweden |
| 7 | Jimmy Connors | 1972-1996 | USA |
| 8 | Ivan Lendl | 1978-1994 | Czechoslovakia |
| 9 | Andre Agassi | 1986-2006 | USA |
| 10 | John McEnroe | 1976-2006 | USA |
| 11 | Andy Murray | 2005-2024 | USA |
| 12 | Boris Becker | 1984-1999 | Germany |
| 13 | Stefan Edberg | 1983-1996 | Sweden |
| 14 | Mats Wilander | 1981-1996 | Sweden |
| 15 | Pancho Gonzales | 1949-1974 | USA |
| 16 | Ken Rosewall | 1956-1980 | Australia |
| 17 | Bill Tilden | 1910-1946 | USA |
| 18 | Jack Kramer | 1937-1954 | USA |
| 19 | John Newcombe | 1960-1981 | Australia |
| 20 | Jim Courier | 1988-2000 | USA |
| 21 | Don Budge | 1932-1961 | USA |
| 22 | Ellsworth Vines | 1930-1940 | USA |
| 23 | Roy Emerson | 1951-1983 | Australia |
| 24 | Arthur Ashe | 1959-1980 | USA |
| 25 | Ilie Năstase | 1966-1985 | Romania |
| 26 | Guillermo Vilas | 1968-1992 | Argentina |
| 27 | Stan Wawrinka | 2002-active | Switzerland |
| 28 | Carlos Alcaraz | 2018-active | Spain |
| 29 | Jannik Sinner | 2018-active | Italy |
| 30 | Daniil Medvedev | 2014-active | Russia |
| 31 | Lleyton Hewitt | 1998-2020 | Australia |
| 32 | Andy Roddick | 2000-2015 | USA |
| 33 | Marat Safin | 1997-2009 | Russia |
| 34 | Patrick Rafter | 1991-2001 | Australia |
| 35 | Gustavo Kuerten | 1995-2008 | Brazil |
| 36 | René Lacoste | 1922-1932 | France |
| 37 | Henri Cochet | 1922-1958 | France |
| 38 | Hans Nüsslein | 1926-1957 | Germany |
| 39 | Gottfried von Cramm | 1931-1952 | Germany |
| 40 | Goran Ivanišević | 1988-2004 | Croatia |
| 41 | Juan Carlos Ferrero | 1988-2012 | Spain |
| 42 | Thomas Muster | 1985-2011 | Austria |
| 43 | Yevgeny Kafelnikov | 1992-2010 | Russia |
| 44 | Carlos Moyá | 1995-2010 | Spain |
| 45 | Juan Martin Del Potro | 2005-2022 | Argentina |
| 46 | Michael Chang | 1988-2003 | USA |
| 47 | Dominic Thiem | 2011-2024 | Austria |
| 48 | Michael Stich | 1988-1997 | Germany |
| 49 | Jaroslav Drobný | 1938-1969 | Czechoslovakia |
| 50 | Pancho Segura | 1939-1970 | Ecuador/USA |
| 51 | Bobby Riggs | 1933-1962 | USA |
| 52 | Sergi Bruguera | 1988-2002 | Spain |
| 53 | Tony Roche | 1963-1979 | Australia |
| 54 | Stan Smith | 1964-1985 | USA |
| 55 | Jan Kodeš | 1966-1983 | Czechoslovakia |
| 56 | Fred Perry | 1929-1959 | England |
| 57 | Lew Hoad | 1950-1973 | Australia |
| 58 | Tony Trabert | 1945-1963 | USA |
| 59 | Frank Sedgman | 1953-1976 | Australia |
| 60 | Stefanos Tsitsipas | 2016-active | Greece |
| 61 | Alexander Zverev | 2013-active | Germany |
| 62 | Jack Crawford | 1926-1951 | Australia |
| 63 | David Ferrer | 2000-2019 | Spain |
| 64 | Tomáš Berdych | 2002-2019 | Czech Republic |
| 65 | Yannick Noah | 1977-1996 | France |
| 66 | Vitus Gerulaitis | 1971-1986 | USA |
| 67 | Pat Cash | 1982-2006 | Australia |
| 68 | Jean Borotra | 1920-1956 | France |
| 69 | Laurence Doherty | 1893-1910 | England |
| 70 | Jo-Wilfried Tsonga | 2004-2022 | France |
| 71 | David Nalbandian | 2000-2013 | Argentina |
| 72 | Manuel Orantes | 1964-1983 | Spain |
| 73 | Miloslav Mečíř | 1982-1990 | Czechoslovakia |
| 74 | Marcelo Ríos | 1994-2004 | Chile |
| 75 | Budge Patty | 1940-1960 | USA |
| 76 | Tom Okker | 1964-1981 | Netherlands |
| 77 | Petr Korda | 1987-2005 | Czech Republic |
| 78 | Tim Henman | 1993-2007 | England |
| 79 | William Larned | 1890-1911 | USA |
| 80 | Tommy Haas | 1996-2018 | Germany |
| 81 | Kei Nishikori | 2007-active | Japan |
| 82 | Alex Corretja | 1991-2005 | Spain |
| 83 | Casper Ruud | 2015-active | Norway |
| 84 | Marin Čilić | 2005-active | Croatia |
| 85 | Anthony Wilding | 1904-1914 | New Zealand |
| 86 | Richard Krajicek | 1989-2003 | Netherlands |
| 87 | Guillermo Coria | 2000-2009 | Argentina |
| 88 | Nikolay Davydenko | 1999-2014 | Russia |
| 89 | Thomas Enqvist | 1991-2005 | Sweden |
| 90 | Milos Raonic | 2008-active | Canada |
| 91 | Andrés Gimeno | 1960-1974 | Spain |
| 92 | Andrés Gómez | 1979-1995 | Ecuador |
| 93 | Adriano Panatta | 1969-1983 | Italy |
| 94 | Andrei Medvedev | 1991-2001 | Ukraine |
| 95 | Andrey Rublev | 2014-active | Russia |
| 96 | Grigor Dimitrov | 2008-active | Bulgaria |
| 97 | Todd Martin | 1990-2004 | USA |
| 98 | Wayne Ferreira | 1989-2005 | S. Africa |
| 99 | Cédric Pioline | 1989-2002 | France |
| 100 | Robin Söderling | 2001-2011 | Sweden |